THE RELATION BETWEEN HEMOLYTIC AND NON-HEMOLYTIC STREPTOCOCCI, AND ITS POSSIBLE SIGNIFICANCE

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The Relation between Hemolytic and Non-hemolytic Streptococci, and Its Possible Significance

1. The relation between hemolytic and non-hemolytic streptococci is orderly and arises from the fact that the former variety is unique while the latter is heterogeneous. 2. Analogous considerations of the classification, distribution, and pathogenicity of the streptococcus group and the pneumococcus and colon-typhoid groups show a definite parallelism. 3. These considerations suggest that uniqu...

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The Conversion of Hemolytic Streptococci to Non-hemolytic Forms

From one strain of hemolytic streptococcus three forms were isolated, which produced three different degrees of hemolysis on the surface of blood agar in the presence of oxygen. The original form was moderately hemolytic; the glossy variant was more hemolytic than the original form; and the third form, obtained by passing the original culture through mice, was non-hemolytic. Under anaerobic con...

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1. Blood cultures from 25 cases of acute rheumatic fever were negative for non-hemolytic streptococci of both the alpha and gamma types. 2. Non-hemolytic (gamma type) streptococci were frequently recovered from the throats of patients with this disease. 3. Similar organisms were recovered just as frequently from the throats of normal individuals. 4. Although these non-hemolytic streptococci wer...

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A Classification of Non-hemolytic Streptococci

1. No connection can be demonstrated between grouping of non-hemolytic streptococci based upon fermentation reactions, and grouping based upon immunological reactions. 2. A classification of non-hemolytic streptococci can be effected by studying the complement fixation reactions between the streptococci and their antisera. 3. The arrangement of the streptococci in such a classification depends ...

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Reactions of Rabbits to Non-hemolytic Streptococci

1. Accompanying and following the evolution of a secondary reaction in the skin of rabbits after inoculation with suitable doses of certain non-hemolytic streptococci there quickly develops a general state of hypersensitiveness or allergy towards these streptococci. 2. This state is made evident by ophthalmic reactions following corneal inoculations, by much increased reactivity of the skin fol...

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ژورنال

عنوان ژورنال: Journal of Experimental Medicine

سال: 1918

ISSN: 1540-9538,0022-1007

DOI: 10.1084/jem.28.2.181